Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment
Joel Gruchot https://orcid.org/0000-0003-4894-4679, Isabel Lewen https://orcid.org/0000-0001-9818-6218, Michael Dietrich https://orcid.org/0000-0002-4055-6711, Laura Reiche https://orcid.org/0000-0002-2358-9925, Mustafa Sindi https://orcid.org/0009-0008-2890-2336, Christina Hecker, Felisa Herrero https://orcid.org/0000-0002-2055-1147, Benjamin Charvet, Ulrike Weber-Stadlbauer https://orcid.org/0000-0002-5278-9993, Hans-Peter Hartung https://orcid.org/0000-0002-0614-6989, Philipp Albrecht https://orcid.org/0000-0001-7987-658X, Hervé Perron https://orcid.org/0000-0002-2551-7685, Urs Meyer https://orcid.org/0000-0001-7244-0345, and Patrick Küry https://orcid.org/0000-0002-2654-1126 [email protected]Authors Info & AffiliationsEdited by Lawrence Steinman, Stanford University, Stanford, CA; received May 16
Scenes From California’s Fast-Moving Oak Fire
A wildfire that erupted in California on Friday expanded ferociously over the weekend, amid scorching temperatures and tinder-dry conditions, consuming nearly 17,000 acres by Monday. The fast-moving Oak Fire, burning west of Yosemite National Park, has forced thousands of residents to evacuate the area. The blaze, California’s biggest wildfire this year, remains only 10 percent
These Are the Most (And Least) Happy States in the U.S. 2023, According to a New Report
Happiness can come from a multitude of factors, from weather to the job market, but when it comes to the state of your well-being, is it really location, location, location?Well, according to a new study, some states are significantly happier than others.A new report by the personal finance platform Wallet Hub ranked the happiest states
AI.com once took you to ChatGPT. Now, it goes to Elon Musk’s xAI
Will someone please tell us who the hell owns AI.com and what they’re doing with it?The domain, which used to direct to ChatGPT, now redirects users to xAI, an AI company owned by Elon Musk. Separate from X Corp, xAI claims on its website that it “will work closely with X,” the social media company
Planning for Data Sovereignty in a Multicloud World
With its roots in privacy law emerging from the UK and Europe, data sovereignty has become a global concern. Increasingly, international trade requires compliance with local data laws—covering nations, states, or other jurisdictions such as the EU. Governments, rather than corporations or hyperscalers, are setting the rules: Not only can they require data to be
Concerned About Childhood Obesity? Intermountain Health Experts Suggest Adopting Healthy Lifestyle
Latest data suggests the prevalence of pediatric obesity is 19.3 percent in the United States, or roughly 14.4 million adolescents and children. In the U.S., increasing rates of children struggling with obesity is bringing the discussion of health and nutrition to the forefront — something Intermountain Health caregivers are hoping will shine a light on the
Actor Sues After Gangster’s Classic TV Lines Used in Video Game
Is it legal to take classic lines from a TV show and use them in a video game without authorization? That is the question being debated in China’s first copyright dispute over lines spoken in a film or TV series.On Monday, the dispute between famous Chinese actor Sun Honglei, 53, and two gaming companies was
Mercatus Marketing Singapore Community Retail Portfolio for $194M
NTUC FairPrice at 71 Kallang Bahru is one of the nine assets in cluster one. (Source: Direct Home) After opening the year selling a trio of mall properties for more than S$2.8 billion, Mercatus Co-operative has headed back to the market with a set of community retail assets carrying a price tag of S$265 million
Aljamain Sterling questions Sean O’Malley vs. Chito Vera 2: ‘Why are we making this a WWE sport?’
Former UFC bantamweight champion Aljamain Sterling understands why charisma is just as big a part of finding success in the UFC as fighting. Still, he can’t fathom why the UFC would skip over other contenders to give Sean O’Malley a rematch with Chito Vera. “Chito’s No. 6, dude, I don’t even…there’s a story line,” Sterling
Accurate proteome-wide missense variant effect prediction with AlphaMissense | Science
Jun Cheng https://orcid.org/0000-0001-5573-9791 [email protected], Guido Novati, Joshua Pan, Clare Bycroft https://orcid.org/0000-0002-1139-0732, Akvilė Žemgulytė, Taylor Applebaum https://orcid.org/0000-0002-6716-8006, Alexander Pritzel, Lai Hong Wong, Michal Zielinski https://orcid.org/0000-0001-5758-5167, Tobias Sargeant https://orcid.org/0000-0002-0909-7182, Rosalia G. Schneider https://orcid.org/0000-0002-6651-2530, Andrew W. Senior https://orcid.org/0000-0002-2401-5691, John Jumper https://orcid.org/0000-0001-6169-6580, Demis Hassabis https://orcid.org/0000-0003-2812-9917, Pushmeet Kohli https://orcid.org/0000-0002-7466-7997 [email protected], and Žiga Avsec https://orcid.org/0000-0002-7790-8936 [email protected]Authors Info & AffiliationsScience19 Sep 2023Vol