Author Correction: Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides

Author Correction: Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides

Correction to: Nature Biotechnology https://doi.org/10.1038/s41587-021-01143-8, published online 6 January 2022.

In the version of this article initially published, two patents were not included in the last paragraph of the “Polyketide production by native PKS hybrid enzymes in D. discoideum” subsection of Results, now reading “Moreover, the G1516R and D1553L substitutions in the S-adenosylmethionine binding site of the MT domain led to the lack of methylation and production of olivetol (6), as is also claimed by two previous patents on the production of methylolivetol and olivetol by expressing the Dictyostelium wild type and mutated PKSs in Saccharomyces cerevisiae1,2. The changes have been made to the HTML and PDF versions of the article.

References

  1. Mookerjee, S., Campbell, A. J., Wiltshire, Z. D. & Chen, K. J. Method and cell line for production of phytocannabinoids and phytocannabinoid analogues in yeast. US patent no. 20200283807A1 (2018).

  2. Mookerjee, S., Campbell, A. J., Wiltshire, Z. D. & Chen, K. J. Method and cell line for production of polyketides in yeast. US patent no. 10975395B2 (2020).

Download references

Author information

Author notes

  1. These authors contributed equally: Christin Reimer, Johann E. Kufs.

Authors and Affiliations

  1. Evolution of Microbial Interactions, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (Leibniz-HKI), Jena, Germany

    Christin Reimer & Falk Hillmann

  2. Faculty of Biological Sciences, Friedrich Schiller University Jena, Jena, Germany

    Christin Reimer & Johann E. Kufs

  3. Biobricks of Microbial Natural Product Syntheses, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (Leibniz-HKI), Jena, Germany

    Johann E. Kufs, Julia Rautschek & Vito Valiante

  4. Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (Leibniz-HKI), Jena, Germany

    Johann E. Kufs & Lars Regestein

Corresponding authors

Correspondence to
Vito Valiante or Falk Hillmann.

About this article

Cite this article

Reimer, C., Kufs, J.E., Rautschek, J. et al. Author Correction: Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides.
Nat Biotechnol (2022). https://doi.org/10.1038/s41587-022-01607-5

Download citation

Read More

Author: Christin Reimer

Leave a Reply